Issa is a Spanish form of the English, Greek, and Hebrew Elizabeth.
Issa is also a form of the Spanish, German, Dutch, English, and Italian Isa.
Issa is not often used as a baby girl name. It is not in the top 1000 names. In 2012, out of the family of girl names directly related to Issa, Elizabeth was the most regularly used.
† English pronunciation for Issa: IY as in "eat (IY.T)" ; S as in "see (S.IY)" ; AA as in "odd (AA.D)"